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Types of Cannabinoids

What Does CBG Do? Does CBG Have Therapeutic Properties?

The potential therapeutic effects of cannabis-derived products make new product innovations like CBG incredibly intriguing.

Finding out what those therapeutic effects are is where the trick lies. With over 113 cannabinoids found to date, it’s almost impossible to keep track of what each of them does. But we’re here to help out.

CBG is an integral part of all cannabinoids. In fact, without CBG, there is no CBD or THC. But what is it exactly?

What is CBG?

CBG is a non-psychoactive cannabinoid. CBG can be found in various cannabis plants, but commercial CBG is usually extracted from hemp.

Hemp carries a negligible amount of THC, the only psychoactive component in cannabis. It is considered federally legal in the U.S. Like cannabidiol (CBD), cannabigerol (CBG) extracts from hemp plants.

CBG is the precursor and known as the ‘mother cannabinoid’ to all other cannabinoids.

CBG is found initially naturally within the plant as CBG-A. This acidic version slowly breaks down into CBG, but the levels of the resulting cannabinoid are relatively low, often kept under 1% per unit of dry weight.

What is CBG Used For?

CBG has been associated with a wide range of benefits and is often used for appetite regulation, sleep pattern modification, and pain management.

However, the benefits of CBG are yet to be clinically proven. Its effect on symptoms of the conditions mentioned above is only anecdotal at the moment.

With that said, CBG has been found to alleviate symptoms of the following health conditions:

1. Inflammatory Bowel Disease: 

CBG reduces inflammation and may help reduce the discomforts caused by inflammatory bowel disease. [3]

2. Glaucoma: 

It’s not a surprise to most that medical cannabis has been used as a treatment for glaucoma for decades now. Because of the relationship between cannabis and glaucoma, researchers believe other cannabinoids like CBG could have similar effects on patients. [4]

3. Bladder Contractility: 

CBG has been proven to be one of the most efficient cannabinoids in treating symptoms of bladder contractility. [5]

4. Neurodegenerative Conditions: 

A 2015 study on the anti-neurodegenerative properties of CBG showed promise using cannabinoids as a potential therapy for neurodegenerative diseases like Huntington’s Disease. [6]

5. Bacterial Infections: 

A 2008 study on CBG and four other cannabinoids suggest that CBG could have a potent antibacterial effect against methicillin-resistant Staphylococcus aureus (MRSA). [7]

Potential Benefits of CBG

While the above describes CBG uses, the potential benefits of CBG are a slightly different topic. The benefits and effects of CBG are the characteristics that set the component apart from other cannabinoids. The

Non-Psychoactive

CBG does not have a psychoactive profile. This means that when you consume CBG, you won't feel 'high' or any intoxicating effects. Making CBG a perfect alternative for consumers that want to explore the therapeutic benefits of CBG & cannabis while remaining clear-headed.

Anti-Inflammatory Effects

An In Vitro Model of Neuro Inflammation has shown that CBG could have anti-inflammatory properties and provide potentially analgesic effects on the body.

Mood-Boosting Effects

CBG intake has been shown to favor the body's production of Anandamide, a chemical that interacts with the Endocannabinoid System and plays an important role in mood regulation. But this relation is purely based on anecdotal evidence and has not been clinically proven.

Stimulating & Modifying Appetite

CBG does not have an effect on appetite like THC with an episode of 'the munchies.' According to a 2016 study on pre-satiated rats, CBG is a well-tolerated appetite stimulant.

Eye Health

By relieving intraocular pressure, CBG has anti-inflammatory effects that could reduce pain symptoms caused by glaucoma. According to researchers, CBG may play a major role in using cannabis as a glaucoma treatment.

Restlessness & Lack of Sleep

Because of its non-psychoactive profile, CBG can be used as a day-time substance. But its anti-inflammatory properties combined with the potential analgesic effects it has on the body make it a great product to use for relaxation purposes. Making it an excellent option for people who have a hard time falling asleep.

Neuroprotective Properties

In a 2015 study on the role of cannabinoids in adult neurogenesis, CBG was found to promote brain cells' growth. Research regarding this subject is extremely positive but is yet to arrive at any conclusive results.

Anxiety & Depression

Marijuana has a high content of THC, which may result in additional anxiety for some users. Because CBG does not have a psychoactive profile, your head remains clear and focused, avoiding any unnecessary fits of anxiety. While a direct effect on pressure has not been clinically proven, the lack of a psychoactive profile speaks volumes of its impact on the body.

Intake Methods & CBG Uses

The FDA does not recognize CBG as a prescription drug, which means that if you decide to consume CBG, you’ll be doing so as a supplement.

CBG seems to be quite scarce as an independent product, and the easiest way to find it is as a part of another product. These are the best ways to start taking CBG:

1. Try a Full-Spectrum CBD Extract

Full-spectrum CBD extracts are made from a combination of all components found in cannabis. With a THC level that stays under 0.3%, full-spectrum extract is still non-psychoactive and completely legal. 

Because it contains different cannabinoids, you will also be ingesting specific amounts of CBG with a full-spectrum extract. Full-spectrum extracts may be used to build your tolerance to CBG before you go with a more pure option.

2. CBG Flower

CBG flower is more widely available than CBG tinctures are. Flower is also a delivery method you might be used to so it won’t feel strange like tinctures or rubs.

3. CBG Tinctures & Other Product Categories

You may find CBG in oils, capsules, drops, topicals, and edibles as you would any other cannabinoid. Sublingual drops have the fastest onset out of all product categories, topicals act in a localized way, and edibles like capsules or gummies have a slower onset but may be more pleasant to consume for some users.

Conclusion

CBG is a non-psychoactive cannabinoid primarily sourced from the hemp plant. CBG is a precursor cannabinoid, which means a natural breakdown makes all other cannabinoids of the natural form of CBG found in the plant.

CBG can be used to cope with a wide variety of symptoms, but most of its benefits remain supported by anecdotal evidence. CBG uses and product category list are as diverse as that of any other cannabinoid product, including finished goods like oils, edibles, topicals, capsules, and vape juices.

Hemmfy articles and blogs are meant to entertain and educate. However, we are not medical professionals and do not intend to give medical advice through them.

The knowledge around CBD and other cannabis-derived products is growing and constantly changing, as does their legal status. Hence, we recommend checking with your local authorities and a licensed physician prior to consumption.

References

[1] Thomas, A., Baillie, G. L., Phillips, A. M., Razdan, R. K., Ross, R. A., & Pertwee, R. G. (2007). Cannabidiol displays unexpectedly high potency as an antagonist of CB1 and CB2 receptor agonists in vitro. British Journal of Pharmacology, 150(5), 613–623. https://doi.org/10.1038/sj.bjp.0707133

[2] Navarro, G., Varani, K., Reyes-Resina, I., Sánchez de Medina, V., Rivas-Santisteban, R., Sánchez-Carnerero Callado, C., Vincenzi, F., Casano, S., Ferreiro-Vera, C., Canela, E. I., Borea, P. A., Nadal, X., & Franco, R. (2018). Cannabigerol Action at Cannabinoid CB1 and CB2 Receptors and at CB1–CB2 Heteroreceptor Complexes. Frontiers in Pharmacology, 9, 1. https://doi.org/10.3389/fphar.2018.00632

[3] Borrelli, F., Fasolino, I., Romano, B., Capasso, R., Maiello, F., Coppola, D., Orlando, P., Battista, G., Pagano, E., Di Marzo, V., & Izzo, A. A. (2013). Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease. Biochemical Pharmacology, 85(9), 1306–1316. https://doi.org/10.1016/j.bcp.2013.01.017

[4] Cross, J. (2006). MEDLINE, PubMed, PubMed Central, and the NLM. Editors’ Bulletin, 2(1), 1–5. https://doi.org/10.1080/17521740701702115

[5] Pagano, E., Montanaro, V., di Girolamo, A., Pistone, A., Altieri, V., Zjawiony, J. K., Izzo, A. A., & Capasso, R. (2015). Effect of Non-psychotropic Plant-derived Cannabinoids on Bladder Contractility: Focus on Cannabigerol. Natural Product Communications, 10(6), 1934578X1501000. https://doi.org/10.1177/1934578x1501000653

Simon Cartagena

Simon Cartagena is a full-time cannabis copywriter. This has led him to write for companies like Hemmfy.com where he acts as Senior Content Writer and other world-renowned cannabis publications. Simon has created Content Marketing strategies and articles that have helped company revenues increase by up to 1,000%. Simon’s goal is to help people understand cannabis in an industry where misinformation seems to be predominant.