THC and CBD Types of Cannabinoids

Cannabis Effects: This Is Why Cannabis Affects Everyone Differently

The adverse side-effects of prescription and over-the-counter drugs for dealing with pain and disease, as well as the negative consequences caused by an overindulgence of socially accepted libations such as alcohol and tobacco, find people looking to nature for relief. 

Cannabis represents an herb that though available since nearly the beginning of time, continues to grow in popularity due to progressive legislation and advanced research. 

Cannabis effects don't measure the same on everyone, however. Whether using a form of cannabis for medicinal or recreational use, it makes sense to understand how this form of relief or libation may affect you.  


What Is Cannabis?

Cannabis and the ECS

Why Individuals Respond Differently to Cannabis

Wrapping Up

What Is Cannabis?

The cannabis or cannabis Sativa plant originated in what we now know as Tibet in the Himalayas. Though native to Central Asia, this sturdy fibrous plant will grow just about anywhere. In addition to medicinal and recreational uses, the industrial hemp version of cannabis also serves as an ecological solution to plastic replacements and textiles for garments, household linens, and other supplies. 

To discuss the effects cannabis has on the body, we need to distinguish the difference between the hemp plant and the marijuana plant. The hemp and marijuana plants derive from the same species of the cannabis Sativa plant. Though both these plants contain hundreds of different compounds and dozens of other cannabinoids, tetrahydrocannabinol or THC represents the cannabinoid that separates the two plants. To qualify as hemp, the plant must contain less than .3% THC. We find THC in marijuana plants in amounts that measure between .5 and 30%. THC contains psychoactive properties and results in a euphoric high, or stoned feeling sought after by recreational users. 

THC also offers some medicinal uses, which explains why medicinal marijuana now enjoys a legal status in the majority of the United States. Cannabidiol or CBD represents the most notable cannabinoid in the hemp plant. The legal status of CBD oil and other CBD products contributes to its success as a growing and profitable industry. CBD effects on the body may be therapeutic without the psychoactive effects derived from marijuana and THC. 

Cannabis and the ECS

Cannabis tolerance and especially THC tolerance may differ in individuals partially due to their endocannabinoid system or ECS condition. The ECS consists of a series of endocannabinoids or small acidic endogenous molecules made up of arachidonic acid, anandamide, and arachidonoyl glycerol. These molecules run throughout the bodies of all mammals. 

The primary function of the ECS involves homeostasis or balance. However, the ECS easily becomes compromised through aging and autoimmune conditions and poor lifestyle choices, including tobacco and alcohol abuse, an unbalanced diet, inadequate sleep, and poor stress management. 

Cannabis may help a sluggish ECS because the system within the plant that maintains the plant's health mimics that of the ECS. The cannabis effect on the body depends on the condition of the individual's ECS and the form of cannabis ingested.

Differences Between Marijuana and Hemp [Pertaining to the ECS]

The research and efforts put into growing marijuana since its legalization for medicinal and recreational purposes accounts for a  much more potent result than the joints passed around at Woodstock. The average THC dose of marijuana in the 1960s and 1970s measured around 10mg, while today's skunkweed and other subspecies may come in between 150 and 300 mg. 

THC possesses a strong affinity for both CB1 and CB2 receptors as it works with the endocannabinoid system. This binding function means that it affects all parts of the brain, including the cerebral cortex, cerebellum, and hippocampus. 

Differences Between Marijuana and Hemp

When properly dosed, marijuana may alleviate symptoms or help manage conditions such as epilepsy, nausea, chronic pain, MS, and more. However, as it metabolizes in the brain, regular or prolonged use of marijuana may also cause memory loss, cognitive problems, diminished motor skills, and paranoia. 

Since CBD does not possess psychoactive properties, it does not penetrate the CB1 and CB2 receptors as enthusiastically as THC and does not come with the extensive laundry list of adverse cannabis effects. Those asking, 'how long do CBD effects last?' will again need to consider their general health condition and other supplements and medications taken when considering their dosage and frequency of CBD use.

Why Individuals Respond Differently to Cannabis 

A couple of things will automatically affect how your system might react to THC or CBD. Of course, the quality and strength of the product and the dose take will impact the results. THC may mimic the effects of alcohol, sedatives, opiates, and even hallucinogenics. If you combine marijuana with other substances, this will also alter the effects of marijuana. 

The condition of a person's ECS may also influence the body's response to either CBD or THC. Those in good health who possess a well-functioning ECS may not notice much difference when taking a CBD gummy for general maintenance or added energy. Someone who experiences unchecked anxiety and stress may report that adding CBD calms them and helps them sleep.

The delivery method of THC and CBD also may significantly impact the speed and effect it produces in an individual. Typically smoking and concentrated tinctures will enter the bloodstream more quickly than, say, gummies or capsules and bring quicker results.

Since marijuana metabolizes so efficiently throughout the brain, those with underdeveloped brains, such as adolescents, will most likely suffer adverse cannabis effects, especially if habitually used. It does not take more than a few uses before marijuana could potentially result in these adverse cannabis effects in teenagers:

  • Negatively altering brain development
  • Suffering grades and poor educational outcomes
  • Chronic respiratory problems
  • Mood swings, depression, or general dissatisfaction with life
  • An increased risk of addiction

Wrapping Up

Chemistry differs from person to person for several reasons. Heredity, lifestyle choices, diet, and many other factors play a role in how your body reacts to cannabis consumption.

When using CBD, one should follow the manufacturer's or their health professional's instructions regarding dosing. Always making sure to increase the dose slowly, incrementally, and only when suggested by a licensed medical professional. 

States that allow medical marijuana hold various mandates to make sure its use stays regulated by medical professionals while recreational users may want to take note of unwanted or adverse effects and adjust their usage accordingly. 

Hemmfy articles and blogs are meant to entertain and educate. However, we are not medical professionals and do not intend to give medical advice through them.

The knowledge around CBD and other cannabis-derived products is growing and constantly changing, as does their legal status. Hence, we recommend checking with your local authorities and a licensed physician prior to consumption.

Simon Cartagena

Simon Cartagena is a full-time cannabis copywriter. This has led him to write for companies like Hemmfy.com where he acts as Senior Content Writer and other world-renowned cannabis publications. Simon has created Content Marketing strategies and articles that have helped company revenues increase by up to 1,000%. Simon’s goal is to help people understand cannabis in an industry where misinformation seems to be predominant.